Table A1.
Sensitivity Analysis of CR: No Age Imputation, Conditioned on Genotype and Phenotype Status of Proband
| Age (years) | Harvard |
UM |
Combined |
|||
|---|---|---|---|---|---|---|
| CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | |
| 30 | 0 | 0 | 0 | 0 | 0 | 0 |
| 40 | 0 | 0.01 | 0 | 0.01 | 0 | 0.01 |
| 50 | 0.26 | 0.72 | 0.26 | 0.61 | 0.26 | 0.68 |
| 60 | 2.59 | 7.04 | 2.59 | 6.03 | 2.59 | 6.65 |
| 70 | 9.49 | 13.63 | 9.49 | 15.01 | 9.49 | 13.27 |
Abbreviations: CR, cumulative risk; MMR, mismatch repair; UM, University of Michigan.