Table A3.
Sensitivity Analysis of CR: No Age Imputation, No Conditioning on Genotype or Phenotype Status of Proband
| Age (years) | Harvard |
UM |
Combined |
|||
|---|---|---|---|---|---|---|
| CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | |
| 30 | 0 | 0 | 0 | 0 | 0 | 0 |
| 40 | 0 | 0.01 | 0 | 0.01 | 0 | 0.01 |
| 50 | 0.26 | 0.63 | 0.26 | 0.60 | 0.26 | 0.61 |
| 60 | 2.59 | 6.16 | 2.59 | 5.88 | 2.59 | 6.03 |
| 70 | 9.49 | 12.82 | 9.49 | 18.89 | 9.49 | 14.44 |
Abbreviations: CR, cumulative risk; MMR, mismatch repair; UM, University of Michigan.