Table A5.
Sensitivity Analysis of CR: Age-Imputed Data, Without Conditioning on Genotype or Phenotype of Proband
| Age (years) | Harvard |
UM |
Combined |
|||
|---|---|---|---|---|---|---|
| CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | CR in Population (%) | CR in MMR Carriers (%) | |
| 30 | 0 | 0 | 0 | 0 | 0 | 0 |
| 40 | 0 | 0.01 | 0 | 0.01 | 0 | 0.01 |
| 50 | 0.26 | 0.60 | 0.26 | 0.56 | 0.26 | 0.58 |
| 60 | 2.59 | 5.94 | 2.59 | 5.56 | 2.59 | 5.76 |
| 70 | 9.49 | 16.16 | 9.49 | 21.69 | 9.49 | 18.39 |
Abbreviations: CR, cumulative risk; MMR, mismatch repair; UM, University of Michigan.