Figure 5.

Global gene expression profiling illustrates the divergence of lung MSCs from lung NG-2 expressing pericyte populations. Global gene profiling was performed to compare Hoechst 33342^lowCD45^neg lung MSCs, ABCG2-eGFP lung MSCs, WT FB and NG-2 ds red lung cells. (A) Heat map depiction of relative levels of genes expressed which were overrepresented in ontogeny and KEGG analysis. Ontogeny groups are indicated. Red indicates high levels and blue indicates low levels of gene expression. (B and C) Demonstrate the expression levels of representative genes selected from the analysis and include the Wnt pathway (wisp1, frzb, tbx 20, dlk1), angiogenesis (Flt1, id1, ephb1, ephb2, epha4, nrp2) and the matrix proteins (col18a1, col14a1).