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. Author manuscript; available in PMC: 2013 May 2.
Published in final edited form as: Cell Mol Bioeng. 2011 Mar 8;4(2):281–301. doi: 10.1007/s12195-011-0162-2

TABLE 2.

Basal reaction flux rates and associated parameters for irreversible reaction fluxes.

Fluxes Flux rate*
Km
Km Ki μ±§ ν± or η±§
φGLC→G6P 1.88 4.06 384,000 210
φF6P→GAP1 1.96 7.83 60 0.33 (−)
φGAP1→PYR 3.90 31.20 27,000 0.33 (−) 3214 (−)
φG6P→GLY 0.21** 0.84 210 3.02 (+)
φGLY→G6P 0.31** 1.24 35,100,000 0.33 (−)
φG6P→R5P 0.07** 0.28 210 3214 (−)
φR5P→F6P–GAP1 0.07** 0.14 4 0.13 (−)§§
φPYR→GAP2 0.38 3.01 200 3.02 (+) 0.0003 (+)
φGLR→G3P2 0.01 0.04 220 3.02 (+)
φALA→PYR 3.08 6.16 1300
φPYR→ALA 1.00 2.00 200
φProteolysis 2.65 2.65
φPYR→ACoA 3.92 23.52 100,000 25 3214 (−)
φFA→FAC 1.71 6.86 15,000 3.02 (+)
φFAC→ACoA 0.44 2.61 14,000 25 3214 (−)
φACoA→FA 0.08** 0.64 25 7.63 (+)§§
φTG→DG;ATGL 3.35 3.35
φTG→DG;HSL 0.65 0.65
φDG→MG;HSL 3.29 6.58 2000
φMG→GLR;HSL 0.33 0.66 200
φMG→GLR;MGL 2.67 29.37 2000
φG3P1–FAC→DG 0.04 0.08 10,500
φG3P2–FAC→DG 0.39 0.77 10,500
φDG–FAC→TG 0.43 0.85 140,000
φDG–DG→TG 0.60 1.20 2000
φMG–MG→DG 0.32 0.64 200
φMG–DG→TG 0.27 0.54 400,000
φACoA→ CO2 7.32 58.57 67,500 0.33 (−) 3214 (−)
φO2→H2O 20.43 81.73 27 0.33 (−) 0.0003 (+)
φATP→ADP 129.0 258.0 3840
φTG→GLR;LPL 0.61 1.22 990,000
*

Values are in μmol min−1 kg wet tissue−1. Vmax,k, maximum rate coefficient. Data are from the reference [21] except for those marked with **, which are from the references [37] and [47].

Values are in μmol kg wet tissue−1 except for the marked (), which are in (μmol kg wet tissue−1)2. Km,k, phenomenological M–M constant for the reactants; Ki,k, phenomenological M–M constant for the product inhibition.

§

Values are dimensionless. μ±, ν± and η±, parameters for the metabolic controllers. Those marked with §§, represent η±.

(+) represents μ+, ν+ or η+ while (−) represents μ, ν or η.