TABLE 2.
Basal reaction flux rates and associated parameters for irreversible reaction fluxes.
Fluxes | Flux rate* |
|
Km† | Ki† | μ±§ | ν± or η±§ | |
---|---|---|---|---|---|---|---|
φGLC→G6P | 1.88 | 4.06 | 384,000‡ | 210 | |||
φF6P→GAP1 | 1.96 | 7.83 | 60 | 0.33 (−) | |||
φGAP1→PYR | 3.90 | 31.20 | 27,000‡ | 0.33 (−) | 3214 (−) | ||
φG6P→GLY | 0.21** | 0.84 | 210 | 3.02 (+) | |||
φGLY→G6P | 0.31** | 1.24 | 35,100,000‡ | 0.33 (−) | |||
φG6P→R5P | 0.07** | 0.28 | 210 | 3214 (−) | |||
φR5P→F6P–GAP1 | 0.07** | 0.14 | 4 | 0.13 (−)§§ | |||
φPYR→GAP2 | 0.38 | 3.01 | 200 | 3.02 (+) | 0.0003 (+) | ||
φGLR→G3P2 | 0.01 | 0.04 | 220 | 3.02 (+) | |||
φALA→PYR | 3.08 | 6.16 | 1300 | ||||
φPYR→ALA | 1.00 | 2.00 | 200 | ||||
φProteolysis | 2.65 | 2.65 | |||||
φPYR→ACoA | 3.92 | 23.52 | 100,000‡ | 25 | 3214 (−) | ||
φFA→FAC | 1.71 | 6.86 | 15,000‡ | 3.02 (+) | |||
φFAC→ACoA | 0.44 | 2.61 | 14,000‡ | 25 | 3214 (−) | ||
φACoA→FA | 0.08** | 0.64 | 25‡ | 7.63 (+)§§ | |||
φTG→DG;ATGL | 3.35 | 3.35 | |||||
φTG→DG;HSL | 0.65 | 0.65 | |||||
φDG→MG;HSL | 3.29 | 6.58 | 2000 | ||||
φMG→GLR;HSL | 0.33 | 0.66 | 200 | ||||
φMG→GLR;MGL | 2.67 | 29.37 | 2000 | ||||
φG3P1–FAC→DG | 0.04 | 0.08 | 10,500‡ | ||||
φG3P2–FAC→DG | 0.39 | 0.77 | 10,500‡ | ||||
φDG–FAC→TG | 0.43 | 0.85 | 140,000‡ | ||||
φDG–DG→TG | 0.60 | 1.20 | 2000 | ||||
φMG–MG→DG | 0.32 | 0.64 | 200 | ||||
φMG–DG→TG | 0.27 | 0.54 | 400,000‡ | ||||
φACoA→ CO2 | 7.32 | 58.57 | 67,500‡ | 0.33 (−) | 3214 (−) | ||
φO2→H2O | 20.43 | 81.73 | 27‡ | 0.33 (−) | 0.0003 (+) | ||
φATP→ADP | 129.0 | 258.0 | 3840 | ||||
φTG→GLR;LPL | 0.61 | 1.22 | 990,000 |
Values are in μmol min−1 kg wet tissue−1. Vmax,k, maximum rate coefficient. Data are from the reference [21] except for those marked with **, which are from the references [37] and [47].
Values are in μmol kg wet tissue−1 except for the marked (‡), which are in (μmol kg wet tissue−1)2. Km,k, phenomenological M–M constant for the reactants; Ki,k, phenomenological M–M constant for the product inhibition.
Values are dimensionless. μ±, ν± and η±, parameters for the metabolic controllers. Those marked with §§, represent η±.
(+) represents μ+, ν+ or η+ while (−) represents μ−, ν− or η−.