Fig. 2.

Crust-MS modulates both the pyloric and gastric mill patterns, increasing the interactions between them, as seen in extracellular recordings from the dorsal lateral ventricular nerve (dlvn), ventral lateral ventricular nerve (vlvn) and medial ventricular nerve (mvn) in the stomatogastric nervous system (STNS) of H. americanus. (A) In control saline, lateral pyloric (LP), pyloric (PY), ventricular dilator (VD) and pyloric dilator (PD) neurons fired in pyloric time. Gastric mill (GM) and lateral gastric (LG) neurons fired in gastric time. (B) Bath application of 10⁻⁶ mol l⁻¹ Crust-MS uniquely modulated the pyloric and gastric mill networks. PD and LP neurons were completely suppressed, whereas PY and VD neurons began firing in a more gastric timed pattern, coordinated with other gastric motor neurons (LG and GM shown). In this preparation, burst duration decreased in the GM and LG neurons; in some preparations, GM burst duration increased or remained the same.