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Tumor burden in mice after mesothelioma cell injection followed by daily injection of PBS or AMD3100. (A) Total tumor number significantly increased in PBS-injected but not in AMD3100-injected mice. (B) Initial higher percentage of tumor spheroids in AMD3100-injected mice compared to control. (C) Greater increasing trend in total tumor area in control than in AMD3100-injected mice. (*p-value ≤ 0.05, student’s t-test)
