Table 3.
Multivariable adjusted hazard ratios and 95% confidence intervals for physical activity and ischemic stroke subtypes
| Poor Physical Activity |
Intermediate Physical Activity |
Ideal Physical Activity |
P for trend |
|
|---|---|---|---|---|
| Total sample | ||||
| Lacunar stroke | ||||
| No. of cases | 101 | 24 | 19 | |
| Model 1 * | 1 | 0.71 (0.45,1.13) | 0.74 (0.45,1.22) | 0.132 |
| Model 2 † | 1 | 0.79 (0.50,1.25) | 0.85 (0.51,1.40) | 0.371 |
| Model 3 ‡ | 1 | 0.85 (0.54,1.36) | 0.95 (0.57,1.59) | 0.695 |
| Cardioembolic stroke | ||||
| No. of cases | 100 | 30 | 20 | |
| Model 1 * | 1 | 0.78 (0.51,1.18) | 0.72 (0.44,1.18) | 0.130 |
| Model 2 † | 1 | 0.82 (0.54,1.25) | 0.77 (0.47,1.27) | 0.237 |
| Model 3 ‡ | 1 | 0.87 (0.57,1.34) | 0.83 (0.50,1.37) | 0.402 |
| Nonlacunar stroke | ||||
| No. of cases | 229 | 81 | 44 | |
| Model 1 * | 1 | 0.87 (0.67,1.13) | 0.66 (0.48,0.92) | 0.014 |
| Model 2 † | 1 | 0.91 (0.70,1.19) | 0.71 (0.51,0.99) | 0.046 |
| Model 3 ‡ | 1 | 0.99 (0.76,1.28) | 0.78 (0.56,1.08) | 0.187 |
| Men | ||||
| Lacunar stroke | ||||
| No. of cases | 44 | 13 | 12 | |
| Model 1 * § | 1 | 0.65 (0.35,1.23) | 0.66 (0.35,1.28) | 0.152 |
| Model 2 † § | 1 | 0.71 (0.37,1.34) | 0.74 (0.38,1.43) | 0.286 |
| Model 3 ‡ § | 1 | 0.74 (0.39,1.40) | 0.80 (0.41,1.55) | 0.403 |
| Cardioembolic stroke | ||||
| No. of cases | 39 | 14 | 15 | |
| Model 1 * § | 1 | 0.68 (0.37,1.27) | 0.87 (0.47,1.60) | 0.504 |
| Model 2 † § | 1 | 0.70 (0.37,1.30) | 0.89 (0.48,1.65) | 0.570 |
| Model 3 ‡ § | 1 | 0.71 (0.38,1.34) | 0.96 (0.51,1.79) | 0.729 |
| Nonlacunar stroke | ||||
| No. of cases | 107 | 45 | 26 | |
| Model 1 * § | 1 | 0.82 (0.57,1.16) | 0.56 (0.36,0.87) | 0.009 |
| Model 2 † § | 1 | 0.84 (0.59,1.21) | 0.59 (0.38,0.92) | 0.019 |
| Model 3 ‡ § | 1 | 0.91 (0.63,1.31) | 0.67 (0.43,1.04) | 0.084 |
| Women | ||||
| Lacunar stroke | ||||
| No. of cases | 57 | 11 | 7 | |
| Model 1 * § | 1 | 0.78 (0.40,1.52) | 0.83 (0.37,1.83) | 0.486 |
| Model 2 † § | 1 | 0.90 (0.46,1.76) | 0.96 (0.43,2.14) | 0.838 |
| Model 3 ‡ § | 1 | 0.97 (0.50,1.91) | 1.14 (0.51,2.56) | 0.814 |
| Cardioembolic stroke | ||||
| No. of cases | 61 | 16 | 5 | |
| Model 1 * § | 1 | 0.90 (0.51,1.59) | 0.47 (0.19,1.18) | 0.126 |
| Model 2 † § | 1 | 0.98 (0.55,1.73) | 0.52 (0.21,1.31) | 0.225 |
| Model 3 ‡ § | 1 | 1.06 (0.59,1.88) | 0.54 (0.21,1.37) | 0.307 |
| Nonlacunar stroke | ||||
| No. of cases | 122 | 36 | 18 | |
| Model 1 * § | 1 | 0.93 (0.64,1.37) | 0.82 (0.50,1.35) | 0.428 |
| Model 2 † § | 1 | 0.99 (0.68,1.46) | 0.88 (0.53,1.45) | 0.665 |
| Model 3 ‡ § | 1 | 1.08 (0.73,1.60) | 0.94 (0.56,1.56) | 0.959 |
*
Adjusted for age, sex and race-center.
†
Adjusted for age, sex, race-center, cigarette-years and education.
‡
Adjusted for age, sex, race-center, cigarette-years, educational level, waist-to-hip ratio, systolic blood pressure, antihypertensive medication use, diabetes, left ventricular hypertrophy, HDL cholesterol, LDL cholesterol, lipoprotein(a), fibrinogen, van Willebrand Factor and white blood cell count.
§
Not adjusted for sex.