Table 2.
Model parameter values and distributions
Infection parameters |
Distributions |
|||
---|---|---|---|---|
Gonorrhoea | Reference | Chlamydia | Reference | |
Probability of infection being symptomatic | ||||
Male |
β (0.9, 0.05) |
[12-15] |
β (0.30, 0.15) |
[12,13] |
Female |
β (0.4, 0.15) |
[12-15] |
β (0.15, 0.08) |
[12,13] |
Duration of latent period (days) |
U (3, 5) |
[13,16-18] |
U (12, 28) |
[13,17,19] |
Duration of asymptomatic infection in the absence of treatment (days) |
Γ (105, 35) |
[12,13,20] |
Γ (220, 188) |
[12,19,21-24]* |
Duration of symptomatic infection in the absence of treatment (days) |
Γ (105, 35) |
[12,13,20] |
Γ (112, 35) |
[12,25] |
Duration of immunity following recovery (days) |
Γ (7, 3.5) |
- |
Γ (45, 15) |
- |
Transmission probability per sex act | ||||
Male to Female |
β (0.2, 0.05) |
[12,21,26,27] |
β (0.16, 0.10) |
[12,19,28,29] |
Female to Male | β (0.4, 0.10) | [12,21,26,30,31] | β (0.12, 0.06) | [12,19,28,29] |
Entries with no references are assumptions. U (l, u) denotes a uniform distribution with lower limit of l and upper limit of u; β (m, σ) denotes a beta distribution with mean of m and standard derivation of σ; Γ (m, σ) denotes a gamma distribution with mean of m and standard derivation of σ. Entries marked with ‘*’ indicate that the parameter has been adjusted in the model calibration process in order to generate realistic prevalences for gonorrhoea and chlamydia.