Table 2.

Metformin inhibits fructose and MG-induced intimal SMC migration

Compound		Wound closure (%)
	0 h	24 h	48 h
Control	0	28.5 ± 1.3	82.2 ± 5.30**
Fructose (30 mM)	0	54.1 ± 1.8	85.3 ± 1.9**
Fructose (30 mM) + Metformin (10 mM)	0	23.6 ± 1.1	73.6 ± 1.4*
MG (100 μM)	0	83.4 ± 0.9	96.7 ± 1.4*
MG (100 μM) + Metformin (10 mM)	0	22.2 ± 6.5	66.4 ± 6.9*

^*P < 0.05 vs. 24 hr, ^**P < 0.01 vs. 24 hr.