Table 2.
Characteristics |
Cohort 1 |
Cohort 2 |
||||
---|---|---|---|---|---|---|
|
MACC1 expression |
MACC1 expression |
||||
Low | High | P-value | Low | High | P-value | |
Age |
|
|
|
|
|
|
≤45 |
44 |
51 |
0.647 |
29 |
49 |
0.504 |
>45 |
65 |
85 |
|
45 |
62 |
|
Menopausal status |
|
|
|
|
|
|
Premenopausal |
56 |
60 |
0.799 |
|
|
|
Postmenopausal |
51 |
51 |
|
|
|
|
Clinical stage |
|
|
|
|
|
|
I |
43 |
38 |
0.001 |
19 |
2 |
<0.001 |
II |
45 |
46 |
|
37 |
43 |
|
III |
15 |
25 |
|
14 |
45 |
|
IV |
5 |
28 |
|
4 |
21 |
|
T classification |
|
|
|
|
|
|
T1 |
61 |
49 |
0.019 |
23 |
13 |
<0.001 |
T2 |
39 |
68 |
|
39 |
53 |
|
T3 |
6 |
12 |
|
11 |
30 |
|
T4 |
3 |
7 |
|
1 |
15 |
|
N classification |
|
|
|
|
|
|
N0 |
67 |
68 |
0.050 |
44 |
26 |
<0.001 |
N1 |
25 |
26 |
|
24 |
54 |
|
N2 |
12 |
29 |
|
4 |
26 |
|
N3 |
5 |
13 |
|
2 |
5 |
|
Distant metastasis |
|
|
|
|
|
|
Yes |
104 |
108 |
<0.001 |
0 |
8 |
0.022 |
No |
5 |
28 |
|
74 |
103 |
|
Estrogen receptor |
|
|
|
|
|
|
Positive |
79 |
95 |
0.653 |
36 |
65 |
0.185 |
Negative |
30 |
41 |
|
38 |
46 |
|
Progesterone receptor |
|
|
|
|
|
|
Positive |
63 |
83 |
0.990 |
43 |
67 |
0.760 |
Negative |
32 |
42 |
|
31 |
44 |
|
Her2 |
|
|
|
|
|
|
Positive |
21 |
22 |
0.862 |
8 |
13 |
0.480 |
Negative |
71 |
79 |
|
36 |
41 |
|
Endocrine therapy |
|
|
|
|
|
|
tamoxifen |
62 |
60 |
0.614 |
|
|
|
No treatment | 45 | 50 |