Table 3.
Univariate and multivariate analyses of various prognostic variables for recurrence-free survival in cohort 1
| |
Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | |
| Age |
|
|
|
|
| ≤45 |
0.202 |
0.719 (0.433-1.193) |
|
|
| >45 |
|
|
|
|
| Menopausal status |
0.768 |
0.915 (0.508-1.648) |
|
|
| Premenopausal |
|
|
|
|
| Postmenopausal |
|
|
|
|
| Tumor size (cm) |
|
|
|
|
| ≤2 |
0.000 |
3.479 (1.881-6.435) |
0.146 |
1.649(0.840-3.237) |
| >2 | ||||
| Lymph node status |
|
|
|
|
| Negative |
<0.001 |
5.424 (2.932-10.036) |
<0.001 |
4.205(2.205-8.017) |
| Positive | ||||
| ER |
|
|
|
|
| Positive |
0.012 |
0.519 (0.310-0.866) |
0.060 |
0.606(0.359-1.021) |
| Negative | ||||
| PR |
|
|
|
|
| Positive |
0.020 |
0.528 (0.308-0.906) |
|
|
| Negative | ||||
| ErbB-2 |
|
|
|
|
| Positive |
0.220 |
1.527 (0.777-3.004) |
|
|
| Negative | ||||
| MACC1 expression |
|
|
|
|
| Positive |
0.000 | 3.021 (1.659-5.501) | 0.006 | 2.378(1.279-4.424) |
| Negative | ||||