Table 4.
Univariate and multivariate analyses of various prognostic variables for overall survival in cohort 1
| |
Univariate analysis |
Multivariate |
||
|---|---|---|---|---|
| P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | |
| Age |
|
|
|
|
| ≤45 |
0.261 |
0.709 (0.389-1.291) |
|
|
| >45 |
|
|
|
|
| Menopausal status |
0.589 |
1.223 (0.590-2.534) |
|
|
| Premenopausal |
|
|
|
|
| Postmenopausal |
|
|
|
|
| Tumor size (cm) |
|
|
|
|
| ≤2 |
<0.001 |
5.930 (2.501-14.064) |
0.027 |
2.833(1.125-7.132) |
| >2 | ||||
| Lymph node status |
|
|
|
|
| Negative |
<0.001 |
5.581 (2.674-11.648) |
0.001 |
3.836(1.786-8.239) |
| Positive | ||||
| ER |
|
|
|
|
| Positive |
0.11 |
0.458 (0.251-0.836) |
0.044 |
0.534 (0.290-0.983) |
| Negative | ||||
| PR |
|
|
|
|
| Positive |
0.076 |
0.557 (0.292-1.064) |
|
|
| Negative | ||||
| ErbB-2 |
|
|
|
|
| Positive |
0.837 |
1.101 (0.440-2.758) |
|
|
| Negative | ||||
| MACC1 expression |
|
|
|
|
| Positive |
0.001 | 3.682 (1.756-7.721) | 0.010 | 2.730(1.277-5.839) |
| Negative | ||||