Table 5.
Univariate and multivariate analyses of various prognostic variables for overall survival in cohort 2
| |
Univariate analysis |
Multivariate |
||
|---|---|---|---|---|
| P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | |
| Age |
|
|
|
|
| ≤45 |
0.808 |
1.061 (0.657-1.713) |
|
|
| >45 |
|
|
|
|
| Tumor size (cm) |
|
|
|
|
| ≤2 |
<0.001 |
3.449 (2.131-5.584) |
<0.001 |
2.834(1.741-4.612) |
| >2 | ||||
| Lymph node status |
|
|
|
|
| Negative |
<0.001 |
3.657 (1.960-6.823) |
0.001 |
2.936(1.540-5.597) |
| Positive | ||||
| ER |
|
|
|
|
| Positive |
0.793 |
0.938 (0.583-1.509) |
|
|
| Negative | ||||
| PR |
|
|
|
|
| Positive |
0.036 |
0.603 (0.375-0.968) |
0.002 |
0.465 (0.286-0.757) |
| Negative | ||||
| ErbB-2 |
|
|
|
|
| Positive |
0.886 |
0.937 (0.383-2.292) |
|
|
| Negative | ||||
| MACC1 expression |
|
|
|
|
| Positive |
<0.001 | 4.564 (2.392-8.709) | 0.001 | 3.190 (1.651-6.163) |
| Negative | ||||