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(A) NC; (B) lentivirus-shRNA#1; (C) NC +5 mmol/L lysine; and (D) lentivirus-shRNA#1+5 mmol/L lysine. *P<0.05. The protein levels of caspases 3 and 9 were significantly upregulated by lentivirus-shRNA#1, and this upregulation was intensified by 5 mmol/L lysine. Neither lentivirus-shRNA#1 nor 5 mmol/L lysine changed the expression of caspase 8 alone. Exposure to both conditions increased the protein level of caspase 8.
