Fig. 1.

Real-time RT-PCR analysis of K1, K5, K10, K14, involucrin, and filaggrin expression under normal proliferation conditions (0.03 mM CaCl₂) for 24 h, with DMSO or 17-AAG (0.5 μM) for 24 h, and under high-Ca²⁺ conditions (6 mM CaCl₂) for 2 or 4 days (D2, D4, respectively) in HaCaT. ^∗P < 0.05, ^∗∗∗P < 0.001.