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. 2013 May 2;8(5):e63206. doi: 10.1371/journal.pone.0063206

Figure 4. Mfn1, Mfn2, OPA1, and Fis1 protein expression in neurons following OGD.

Figure 4

Representative western blots are shown for Mfn1 (A), Mfn2 (C), OPA1 (E), and Fis1 (G) with their corresponding β-actin blots. Panels B, D, F, and H show relative intensity bar graphs for the same proteins as means ± s.e.m. of n≥3 independent experiments. Mfn1 increased after OGD, whereas Mfn2 decreased after three, but did not change after one h OGD. OPA1 did not change significantly following OGD. Fis1 protein expression does not change following OGD in neurons. *p<0.05 ***p<0.001 vs. control, n≥3 independent experiments. mitofusin1 = Mfn1, mitofusin2 = Mfn2, optic atrophy-1 protein = OPA1, OGD = oxygen-glucose deprivation.