Table 1.

Concentrations of tryptophan, kynurenine, kynurenine to tryptophan ratio (Kyn/Trp) and neopterin in the supernatant of unstimulated PBMC and in cells stimulated with 10 μg/ml PHA for 48 h. Results shown are the mean values ± SEM of three independent experiments run in duplicates.

	Tryptophan (μM)	Kynurenine (μM)	Kyn/Trp (μmol/mmol)	Neopterin (nM)
Unstimulated	29.9 ± 6.2	2.4 ± 0.9	99.2 ± 46.6	3.8 ± 0.1
PHA (10 μg/ml)	1.9 ± 1.1*	14.3 ± 0.7*	12408 ± 4379*	20.1 ± 1.4*

^*p < 0.05, compared to unstimulated cells.