Table 1. Clinical data of analyzed study groups with “mean ± standard deviation (median)” and statistical analysis of their influence on CSF S-ASM activity in a general linear model.
| GLM for S-ASM in CSF | |||||
| missing values (A/B) | F | p | |||
| study (n) | A (20) | B (22) | – | 5.605 | 0.025 |
| sex (female/male) | 10/10 | 13/9 | 0/0 | 0.005 | 0.943 |
| Age (years) | 46.3±18.3 (42.3) | 43.9±16.6 (48.5) | 0/0 | 0.953 | 0.338 |
| CSF cell count (1/µl) | 1.65±1.18 (1) | 1.48±1.69 (1) | 0/1 | 0.162 | 0.691 |
| CSF protein (mg/l) | 320±87 (294) | 366±120 (340) | 0/0 | 1.596 | 0.217 |
| CSF albumin (mg/l) | 210±70 (189) | 215±90 (204) | 0/0 | 1.897 | 0.180 |
| CSF lactate (mmol/l) | 1.82±0.36 (1.72) | 1.49±0.30 (1.50) | 0/4 | 1.127 | 0.298 |
| S-ASM activity in CSF (fmol/h/µl) | 136±39 (128) | 265±124 (232) | 0/0 | – | – |
| S-ASM activity in serum (fmol/h/µl) | not available | 198±78 (183) | 20/0 | – | – |
| plasma CRP (mg/l) | 4.4±3.7 (3.1) | 23.1±44.1 (3.2) | 1/1 | 1.342 | 0.257 |