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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Drug Discov Today. 2013 Jan 20;18(0):495–501. doi: 10.1016/j.drudis.2013.01.008

Figure 1.

Figure 1

[LM1]Schematic representation of the single-target and multitarget drug discovery paradigms. Although one ligand (key) compound might fit and operate a single target (lock), diseases are associated with complex biological processes and, in several cases, with multiple targets, which are more difficult to ‘unlock’.