Table I.
Characteristics of patients included and excluded from analysis. Numbers in parentheses are percentages of included or excluded patients in that category, unless indicated otherwise. Fisher’s exact test (categorical variable with two categories), chi-square test (categorical variable with three or more categories) and Wilcoxon test (continuous variable) were used to test for differences in patient characteristics between included and excluded.
| Variable | Category | Excluded | Included | Total | p-value |
|---|---|---|---|---|---|
| Total | 207 | 353 | 560 | – | |
| Age | Mean (SD) | 60.0(13.0) | 60.6(13.3) | 60.3(13.2) | 0.665 |
| Median (Q1,Q3) | 60 (51,70) | 61 (52,69) | 61 (52,69) | ||
| [Min, Max] | [1,91] | [17,98] | [1,98] | ||
| Age Category | <=64 | 124(59.9) | 205(58.1) | 329(58.8) | 0.063 |
| >64 | 80(38.6) | 148(41.9) | 228(40.7) | ||
| Unknown | 3(1.4) | 0(0.0) | 3(0.5) | ||
| Gender | Male | 156(75.4) | 252(71.4) | 408(72.9) | 0.326 |
| Female | 51(24.6) | 101(28.6) | 152(27.1) | ||
| Race | White | 162(78.3) | 301(85.3) | 463(82.7) | 0.053 |
| Hispanic | 11(5.3) | 19(5.4) | 30(5.4) | ||
| Black | 29(14.0) | 31(8.8) | 60(10.7) | ||
| Other | 5(2.4) | 2(0.6) | 7(1.2) | ||
| Site | Oral cavity | 85(41.1) | 156(44.2) | 241(43.0) | 0.353 |
| Oropharynx | 47(22.7) | 80(22.7) | 127(22.7) | ||
| Hypopharynx | 16(7.7) | 23(6.5) | 39(7.0) | ||
| Larynx | 43(20.8) | 73(20.7) | 116(20.7) | ||
| Salivary glands | 1(0.5) | 0(0.0) | 1(0.2) | ||
| Other | 13(6.3) | 18(5.1) | 31(5.5) | ||
| Multiple | 0(0.0) | 3(0.8) | 3(0.5) | ||
| Unknown | 2(1.0) | 0(0.0) | 2(0.4) | ||
| PT Stage | T1 | 55(26.6) | 76(21.5) | 131(23.4) | 0.000 |
| T2 | 38(18.4) | 127(36.0) | 165(29.5) | ||
| T3 | 26(12.6) | 61(17.3) | 87(15.5) | ||
| T4 | 24(11.6) | 79(22.4) | 103(18.4) | ||
| TX or Tis | 4(1.9) | 9(2.5) | 13(2.3) | ||
| Unknown | 60(29.0) | 1(0.3) | 61(10.9) | ||
| PN Cat | N0 | 41(19.8) | 130(36.8) | 171(30.5) | 0.000 |
| N1 | 20(9.7) | 48(13.6) | 68(12.1) | ||
| N2 | 51(24.6) | 121(34.3) | 172(30.7) | ||
| N3 | 0(0.0) | 3(0.8) | 3(0.5) | ||
| NX | 39(18.8) | 50(14.2) | 89(15.9) | ||
| Unknown | 56(27.1) | 1(0.3) | 57(10.2) | ||
| Treatment | Surgery Only | 21(10.1) | 110(31.2) | 131(23.4) | 0.000 |
| Surgery + postoperative therapy | 32(15.5) | 172(48.7) | 204(36.4) | ||
| Salvage surgery | 14(6.8) | 65(18.4) | 79(14.1) | ||
| Unknown | 140(67.6) | 6(1.7) | 146(26.1) | ||
| Smoking | Never smoked | 36(17.4) | 66(18.7) | 102(18.2) | 0.377 |
| Pipe or cigar only | 7(3.4) | 15(4.2) | 22(3.9) | ||
| Cigarette: <20 pack-yrs | 31(15.0) | 38(10.8) | 69(12.3) | ||
| Cigarette: 20–40 pack-yrs | 44(21.3) | 96(27.2) | 140(25.0) | ||
| Cigarette: >40 pack-yrs | 82(39.6) | 131(37.1) | 213(38.0) | ||
| Unknown | 7(3.4) | 7(2.0) | 14(2.5) | ||
| Alcohol | <10 oz/wk | 108(52.2) | 186(52.7) | 294(52.5) | 0.531 |
| 10–32 oz/wk | 34(16.4) | 70(19.8) | 104(18.6) | ||
| >32 oz/wk | 50(24.2) | 69(19.5) | 119(21.2) | ||
| Unknown | 15(7.2) | 28(7.9) | 43(7.7) | ||