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. 2013 Mar 15;288(18):12489–12499. doi: 10.1074/jbc.M113.456541

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Models of the fluorogenic peptides bound in the active site of MarP. The fluorescent substrates WKLL-AMC (A) and MCA-PSLIAKWV-K(DNP) (B) (shown as sticks) are modeled in the MarP active site according to their observed cleavage positions. The fluorescent MCA is highly solvent-exposed and could not be modeled accurately. Positively charged, negatively charged, and neutral regions of the protein surface are shown in blue, red, and white, respectively. Side chains and the AMC group are labeled.