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. 2013 May;29(5):273–279. doi: 10.1016/j.tig.2012.11.001

Figure 1.

Figure 1

Different criteria for defining universally conserved genes. When 1000 genomes are compared via comparative genomics, the number of orthologous genes falls to 0 (left), but this number can increase to about 500 persistent genes by comparing orthologs that belong to a quorum of a similar or different genomes from evolutionarily distinct bacteria, above a threshold computed using a measure that retains frequent genes that tend to cluster together (right).