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. 2013 May 3;7:85. doi: 10.3389/fncir.2013.00085

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Copyright © 2013 Tsubo, Isomura and Fukai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Functional activity in identified motor cortex neurons. (A) Juxtacellularly identified layer 5 pyramidal cell that exhibited hold-related activity. Left, visualized soma and dendrites (black) and axons (red). Right, recorded spike waveforms (top) and functional spike activity histogram aligned with the onset of lever pull movement (0 s). (B) Layer 5 pyramidal cell with movement-related activity. (C) Layer 5 fast-spiking (FS) basket cell with movement-related activity. Bottom, fluorescent images for Neurobiotin (NB) and parvalbumin (PV). [Modified from Isomura et al. (2009)].