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. Author manuscript; available in PMC: 2013 May 3.
Published in final edited form as: Cancer Res. 2009 Jan 20;69(3):1143–1149. doi: 10.1158/0008-5472.CAN-08-3499

Figure 2.

Figure 2

PMS2 loss destabilizes tetranucleotide repeats. Points, mutation rate of an independent LCL721 or 1261 clone bearing a tetranucleotide-containing oriP-tk shuttle vector. n = 10, 721/TTCC; n = 4, 721/TTTC; n = 6, 1261/TTCC; n = 6, 1261/TTTC. Outliers not shown on graph: 721/TTCC, 3.16 × 10−3; 1261/TTCC, 3.31 × 10−2. Data were analyzed statistically using the nonparametric Wilcoxon-Mann-Whitney test.