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PMS2 is biased toward repair of [TTCC/AAGG] expansions but has little effect on the deletion rate at the microsatellite. A, the proportion of mutants that contained expansions at the microsatellite was multiplied by the median mutation frequency to obtain the expansion mutation rate. B, the proportion of mutants that contained deletions at the microsatellite was multiplied by the median mutation frequency to obtain the deletion mutation rate. Hatched bars, LCL721; solid bars, LCL1261.
