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The replicative checkpoint prevents MMS-induced HR foci during S phase. (A–C) Rad52 foci accumulation in mrc1AQ (A), rad9Δ (B), and mrc1AQ rad9Δ (C) cells transformed with pWJ1344 (RAD52-YFP), synchronized in G1, and released at 16°C into fresh medium with 0.05 or 0.01% MMS. The average and s.e.m. are shown.
