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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Nucl Med Biol. 2013 Feb 1;40(3):351–360. doi: 10.1016/j.nucmedbio.2013.01.001

Fig. 1.

Fig. 1

Design and synthesis of PC1001. Reagents and conditions: i, a. N-hydroxysuccinimide, DCC, CH2Cl2, rt,12 h; b. tBoc-lysine, 0.1 N sodium borate buffer, pH 8.5, 4° C, 12 h; c. pre-chilled 95% TFA, 4°C, 2 h. ii, DOTA-SulfoNHS (structure shown above), 0.1 N sodium borate buffer, pH 8.5, 12 h. iii, CuCl2 or 64CuCl2, DI H2O, rt, 10 min.