Table 2.
Differences in Aggregate versus Day Level Analysis of the relationship between Methamphetamine Use and HIV Medication Non-Adherence (n = 210)
| Negative Binomial Regression Approach (Aggregate level analysis. Number of methamphetamine use days predicts number of days of medication non-adherence)
| ||||
|---|---|---|---|---|
| β | Exp. β | 95% CI | p | |
|
|
||||
| Intercept | 1.34 | 3.82 | 3.08–4.74 | <.001 |
| Number methamphetamine days | 0.02 | 1.02 | 0.97–1.08 | .42 |
| Likelihood Ratio χ2 (1, n = 210) = 0.67, p = .42 | ||||
| Generalized Estimated Equation Approach (Day level analysis. Predicts odds of HIV medication non-adherence on a day methamphetamine was used)
| ||||
|---|---|---|---|---|
| β | Exp. β | 95% CI | p | |
|
|
||||
| Intercept | −1.07 | 0.34 | 0.31–0.38 | <.001 |
| Methamphetamine day | 0.83 | 2.30 | 1.90–2.78 | <.001 |
| Non-methamphetamine day | 1 | 0 | ||