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. 2013 Mar 13;33(11):4976–4987. doi: 10.1523/JNEUROSCI.3026-12.2013

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Figure 10. — Effect of β4 peptide on lidocaine-mediated suppression of firing in CA3 pyramidal neurons in slices. A, Action potentials in a peptide-free CA3 neuron evoked by a 250 pA current injection before (left) and after (right) perfusion of 100 μm lidocaine. B, Same as A in a different neuron containing the β4 peptide. C, Spike raster for multiple current injections for the cell in A. D, Spike raster for multiple current injections for the cell in B. E, Overlay of boxed regions in A and B, for control solutions (top) and lidocaine solutions (bottom). F, Summary of the number of spikes (left) and the percentage of spikes (right) lost in lidocaine for control (peptide-free) and β4 peptide-containing cells. * p < 0.05.