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Pharmacokinetics of SAR 1118 in the cornea. A single drop (5 μL) of lifitegrast (5%, 1%, or 0.1%) was applied to the intact cornea 15, 3, and 1 h before euthanasia and corneal dissection. The presence of lifitegrast was determined by liquid chromatography–mass spectrometry. Data are mean±SD of 5 mice per group.
