Table 2.

Genes and SNPs Studied

SNP	Gene	Location	Position	Base Substitution	Amino Acid Position	Amino Acid Substitution
rs2071746	HMOX1	Promoter	−413	A → T	NA	NA
rs2071747	HMOX1	Exon 1	99	G → C	7	Asp → His
rs2779249	NOS2A	Promoter	974	C → A	NA	NA
rs2297518	NOS2A	Exon 16	2087	G → A	608	Ser → Leu
rs11549465	HIF1A	Exon 12	2148	C → T	582	Pro → Ser
rs1801320	RAD51	Promoter	−135	G → C	NA	NA
rs11226	RAD52	Promoter	−2259	C → T	NA	NA
rs1042522	TP53	Exon 4	412	C → G	72	Pro → Arg
rs1805388	LIG4	Exon 2	261	C → T	9	Thr → Ile
rs1062557	GRP	Exon 1	108	C → A	4	Arg → Ser
rs1801516	ATM	Exon 37	5942	G → A	1853	Asp → Asn
rs16941	BRCA1	Exon 10	3345	A → G	1038	Glu → Gly
rs16942	BRCA1	Exon 10	3780	G → A	1183	Arg → Lys
rs144848	BRCA2	Exon 10	1341	T → G	372	Asn → His
rs1799782	XRCC1	Exon 6	700	C → T	194	Arg → Trp
rs25489	XRCC1	Exon 9	959	G → A	280	Arg → His
rs25487	XRCC1	Exon 10	1316	G → A	399	Arg → Gln
rs3218536	XRCC2	Exon 3	649	G → A	188	Arg → His
rs861539	XRCC3	Unknown	1045	C → T	241	Thr → Met
rs4880	SOD2	Unknown	201	T → C	16	Val → Ala
rs13181	ERCC2	Exon 23	2298	G → T	751	Lys → Gln
rs2227928	ATR	Exon 4	754	C → T	211	Thr → Met
rs2229032	ATR	Exon 43	7396	G → A	2425	Arg → Gln
rs1130409	APEX1	Exon 5	776	G → T	148	Glu → Asp
rs26279	MSH3	Unknown	3386	G → A	1045	Ala → Thr
rs184967	MSH3	Unknown	3099	G → A	949	Arg → Gln
rs1799977	MLH1	Unknown	715	A → G	219	Ile → Val
rs3790566	IL12RB2	Intron	NA	T → C	NA	NA
rs3790567	IL12RB2	Intron	NA	A → G	NA	NA
rs3790568	IL12RB2	Intron	NA	G → A	NA	NA
rs2230806	ABCA1	Unknown	969	G → A	219	Arg → Lys
rs2253304	ABCA1	Intron	NA	A → G	NA	NA
rs2487058	ABCA1	Intron	NA	C → T	NA	NA

Abbreviations: A = adenine; C = cytosine; G = guanine; NA = not applicable; SNP = single nucleotide polymorphism; T = thymine.