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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Psychiatr Res. 2013 Mar 8;47(6):835–842. doi: 10.1016/j.jpsychires.2013.02.006

Table 4.

Mild moderating effects by 5-HTTLPR genotype and by TBI status on the association between the Perceived Limitations for Social Reintegration (CRIS-PL) score and the Connor-Davidson Resilience Scale (CDRISC) score, prior to controlling for the co-morbid severity of PTSD, Depression, and TBI symptoms.

Step Model Standardized β P-value*
1 5-HTTLPR Genotypea .355 .003

2 5-HTTLPR Genotypea .298 .011
TBI Statusb −.297 .011

3 5-HTTLPR Genotypea .151 .337
TBI Statusb −.379 .004
Genotypea by TBI Statusb Interaction .215 .179

4 5-HTTLPR Genotypea .023 .854
TBI Statusb .015 .896
Genotypea by TBI Statusb Interaction .184 .138
Co-Morbidity Factorc −.711 < .001

5 5-HTTLPR Genotypea .106 .593
TBI Statusb .025 .831
Genotypea by TBI Statusb Interaction .125 .450
Co-Morbidity Factorc −.729 < .001
Genotypea by TBI Co-Morbidity Factorc Interaction .084 .591

6 5-HTTLPR Genotypea .154 .402
TBI Statusb .016 .883
Genotypea by TBI Statusb Interaction .020 .896
Co-Morbidity Factorc −.366 .017
Genotypea by TBI Co-Morbidity Factorc Interaction .136 .350
CRIS-PLd .464 .001

7 (Constant) - .334
5-HTTLPR Genotypea .202 .783
TBI Statusb −.451 .387
Genotypea by TBI Statusb Interaction −.008 .963
Co-Morbidity Factorc −.331 .043
Genotypea by TBI Co-Morbidity Factorc Interaction .125 .554
CRIS-PLd .374 .053
Genotypea by CRIS-PLd Interaction .445 .360
TBI Statusb by CRIS-PLd Interaction −.039 .964
*

Hierarchical Linear Regression

Dependent Variable: Connor-Davidson Resilience Scale (CDRISC) score.

a

5-HTTLPR Genotype: coded as 0 = L′ carrier, 1 = S′S′.

b

TBI Status: coded as 0 = no Traumatic Brain Injury (TBI), 1 = with TBI.

c

Co-Morbidity Factor is the single derived factor score accounting for the high inter-correlation between the PCL-C total score, CES-D total score, and NBSI total score.

d

Community Reintegration of Service Members Instrument - Perceived Limitations in Community Reintegration subscale.