Table 4.
Mild moderating effects by 5-HTTLPR genotype and by TBI status on the association between the Perceived Limitations for Social Reintegration (CRIS-PL) score and the Connor-Davidson Resilience Scale (CDRISC) score, prior to controlling for the co-morbid severity of PTSD, Depression, and TBI symptoms.
Step | Model | Standardized β | P-value* |
---|---|---|---|
1 | 5-HTTLPR Genotypea | .355 | .003 |
| |||
2 | 5-HTTLPR Genotypea | .298 | .011 |
TBI Statusb | −.297 | .011 | |
| |||
3 | 5-HTTLPR Genotypea | .151 | .337 |
TBI Statusb | −.379 | .004 | |
Genotypea by TBI Statusb Interaction | .215 | .179 | |
| |||
4 | 5-HTTLPR Genotypea | .023 | .854 |
TBI Statusb | .015 | .896 | |
Genotypea by TBI Statusb Interaction | .184 | .138 | |
Co-Morbidity Factorc | −.711 | < .001 | |
| |||
5 | 5-HTTLPR Genotypea | .106 | .593 |
TBI Statusb | .025 | .831 | |
Genotypea by TBI Statusb Interaction | .125 | .450 | |
Co-Morbidity Factorc | −.729 | < .001 | |
Genotypea by TBI Co-Morbidity Factorc Interaction | .084 | .591 | |
| |||
6 | 5-HTTLPR Genotypea | .154 | .402 |
TBI Statusb | .016 | .883 | |
Genotypea by TBI Statusb Interaction | .020 | .896 | |
Co-Morbidity Factorc | −.366 | .017 | |
Genotypea by TBI Co-Morbidity Factorc Interaction | .136 | .350 | |
CRIS-PLd | .464 | .001 | |
| |||
7 | (Constant) | - | .334 |
5-HTTLPR Genotypea | .202 | .783 | |
TBI Statusb | −.451 | .387 | |
Genotypea by TBI Statusb Interaction | −.008 | .963 | |
Co-Morbidity Factorc | −.331 | .043 | |
Genotypea by TBI Co-Morbidity Factorc Interaction | .125 | .554 | |
CRIS-PLd | .374 | .053 | |
Genotypea by CRIS-PLd Interaction | .445 | .360 | |
TBI Statusb by CRIS-PLd Interaction | −.039 | .964 |
Hierarchical Linear Regression
Dependent Variable: Connor-Davidson Resilience Scale (CDRISC) score.
5-HTTLPR Genotype: coded as 0 = L′ carrier, 1 = S′S′.
TBI Status: coded as 0 = no Traumatic Brain Injury (TBI), 1 = with TBI.
Co-Morbidity Factor is the single derived factor score accounting for the high inter-correlation between the PCL-C total score, CES-D total score, and NBSI total score.
Community Reintegration of Service Members Instrument - Perceived Limitations in Community Reintegration subscale.