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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Clin Pharmacol Ther. 2012 Aug 1;92(3):287–290. doi: 10.1038/clpt.2012.114

Figure 1.

Figure 1

Intestinal fluid transporting mechanisms. Lower left: crypt–villus unit in the small intestine, comprising basal crypt stem cells, enterocytes, enterochromaffin cells (EC cells), and goblet cells. Right: crypt secretory cell with luminal (top) and basal (bottom) transporters, ion channels, and second messengers. Left: villus absorptive cell with luminal (top) and basal (bottom) transporters. cAMP, cyclic adenosine monophosphate; cGMP, cyclic guanosine monophosphate; CaCC, Ca2+-activated Cl channel; CFTR, cystic fibrosis transmembrane conductance regulator; STa, heat-stable.