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Loc285194 inhibits tumor growth in a xenograft mouse model. (A) Tumor growth curve. HCT-116 WT cells were transfected with vector or loc285194 and then injected into nude mice as described in ‘Materials and Methods’ section. Tumor growth was measured from day 7 after injection of tumor cells. Error bars represent SEM, n = 10. **P < 0.01. (B) Tumor weight when tumors were harvested. Error bars represent SEM, n = 10. *P < 0.05. (C) Total number of tumors after removal from mice.
