Figure 7.
Proposed 3D model of truncated DENV-MINI RNA. The internally deleted DENV-MINI RNA is depicted (A) in its entirety or (B) highlighting the proximal 5′- and 3′-UTRs. Specific RNA domains are color-coded as shown in the key. The cis-acting motifs are labeled as follows: SLA TL, stem–loop A top loop; SLA SSL, stem–loop A side stem–loop; 3′ SL, 3′ stem–loop; dsUAR, double-stranded upstream of AUG region; PK, pseudoknot; TL, top loop. For clarity, the remainder of the RNA molecule is colored in gray.
