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Reporters with high Cbf1: Pho4 affinity ratios show a sensitivity to induction that is anomalously high based on the simple Pho4 + Cbf1 model (X’s), but are explained well a model that assumes a role for bound Cbf1 in shifting promoter chromatin structures toward a more accessible state (circles). Sensitivities were calculated as described in the text. Colors indicate the NA (green), NC (blue), NG (yellow) and NT (red) reporters as in other figures.
