. 2012 Mar;9(1):63–72. doi: 10.3969/j.issn.2095-3941.2012.01.012

Table 2. Combined ORs (95% CI) of subgroups for miR-196a-2 rs11614913.

Subgroup	No. of study	CC vs. TT		CT vs. TT		Dominant model^a		Recessive model^b		Additive model^c
Subgroup	No. of study	OR (95% CI)	Ph	OR (95% CI)	Ph	OR (95% CI)	Ph	OR (95% CI)	Ph	OR (95% CI)	Ph
Total	27	1.23(1.08-1.39)^r	<0.00001	1.15(1.05-1.27)^r	0.0002	1.17(1.06-1.30)^r	<0.0001	1.06(0.97-1.16)^r	<0.0001	1.08(1.01-1.14)^r	<0.00001
Cancer Type
Lung	4	1.26(1.07-1.49)^f	0.26	1.15(1.00-1.33)^f	0.13	1.19(1.04-1.36)^f	0.21	1.07(0.85-1.35)^r	0.07	1.12(1.03-1.22)^f	0.15
Liver	4	1.31(0.87-1.95)^r	0.006	1.11(0.87-1.43)^r	0.08	1.19(0.88-1.61)^r	0.01	1.17(0.91-1.49)^r	0.07	1.14(0.93-1.40)^r	0.006
Breast	5	1.23(0.92-1.65)^r	0.01	1.11(0.98-1.25)^f	0.13	1.15(0.93-1.42)^r	0.03	1.10(1.00-1.21)^f	0.15	1.09(0.96-1.24)^r	0.02
Colorectrol	4	1.44(1.18-1.75)^f	0.28	1.17(0.99-1.38)^f	0.19	1.25(1.06-1.46)^f	0.20	1.30(1.10-1.53)^f	0.38	1.20(1.08-1.32)^f	0.28
Gastric	2	1.24(0.94-1.65)^f	0.31	1.07(0.85-1.34)^f	0.85	1.12(0.90-1.39)^f	0.70	1.22(0.96-1.55)^f	0.16	1.12(0.98-1.28)^f	0.23
Esophageal	2	1.22(0.26-5.72)^r	<0.00001	1.19(0.29-4.81)^r	<0.00001	1.20(0.28-5.11)^r	<0.00001	1.05(0.63-1.74)^r	0.02	1.05(0.55-2.00)^r	<0.00001
Other	6	0.98(0.82-1.16)^f	0.63	1.19(1.02-1.38)^f	0.29	1.10(0.96-1.27)^f	0.53	0.82(0.73-0.92)^f	0.33	0.95(0.88-1.02)^f	0.78
Ethnicity
Asian	17	1.27(1.11-1.46)^r	0.001	1.16(1.04-1.28)^r	0.005	1.19(1.07-1.32)^r	0.002	1.15(1.04-1.27)^r	0.03	1.12(1.05-1.20)^r	0.005
Caucasian	10	1.14(0.86-1.51)^r	0.0005	1.18(0.92-1.51)^r	<0.00001	1.16(0.90-1.50)^r	0.0007	0.93(0.79-1.08)^r	0.004	0.98(0.87-1.11)^r	0.0004
Control Source
PB	9	1.24(1.11-1.39)^f	0.53	1.04(0.95-1.14)^f	0.46	1.10(1.01-1.20)^f	0.47	1.09(0.93-1.27)^r	0.008	1.07(0.99-1.16)^r	0.07
HB	12	1.18(0.96-1.47)^r	0.0009	1.17(1.00-1.37)^r	0.01	1.17(0.99-1.38)^r	0.003	1.03(0.89-1.20)^r	0.006	1.07(0.97-1.19)^r	0.0008
NC	6	1.33(0.90-1.95)^r	<0.00001	1.32(0.98-1.78)^r	0.0003	1.32(0.96-1.83)^r	<0.0001	1.09(0.92-1.29)^r	0.03	1.11(0.95-1.31)^r	<0.0001
Lab test method
PCR-RFLP	15	1.27(1.15-1.41)^f	0.12	1.11(1.02-1.21)^f	0.35	1.16(1.07-1.25)^f	0.24	1.10(0.95-1.26)^r	0.0004	1.09(1.01-1.18)^r	0.005
Others	12	1.14(0.92-1.41)^r	<0.00001	1.17(0.98-1.39)^r	<0.00001	1.16(0.97-1.39)^r	<0.00001	1.03(0.92-1.16)^r	0.01	1.06(0.96-1.16)^r	<0.0001

Ph: P-value of Q-test for heterogeneity test; ^a, Dominant model (CT+CC vs. TT); ^b, Recessive model(CC vs. TT+CT); ^c, Additive model(C vs. T); f, fixed model; r, random model.