Table 11. Hematological and biochemical profile of HCC cases and controls.
| Parameters | HCC (n=357) | Controls† (n=357) | P |
|---|---|---|---|
| Hemoglobin (g/dL) | 11.60± 2.10 | 11.30±2.80 | 0.1060 |
| <10 mg/dL (%) | 121 (33.89) | 100 (28.0) | 0.1050 [OR=1.32(0.95-1.83)] |
| WBC (×103 /mm3) | 6.60±0.40 | 6.50±0.20 | 0.0001* |
| DLC-P (%) | 64.50±5.10 | 63.50±7.40 | 0.0359 |
| DLC-L (%) | 30.90±4.80 | 32.60±7.60 | 0.0004* |
| DLC-E (%) | 3.05±1.40 | 2.90±5.10 | 0.5922 |
| DLC-M (%) | 1.50±0.80 | 1.90±1.80 | 0.0001* |
| Platelet (×104/µL) | 1.80±0.90 | 1.40±0.50 | 0.0001* |
| <1.5 lac/ µL (%) | 115 (32.21) | 105 (29.41) | 0.4650 [OR=1.14 (0.82-1.59)] |
| INR | 1.05±0.40 | 1.00±0.20 | 0.0350 |
| Creatinine (mg/dL) | 1.50±3.20 | 1.06±0.50 | 0.0105 |
| >1.2 mg/dL (%) | 101 (28.29) | 69 (19.33) | 0.0060* [OR=1.65 (1.14-2.37)] |
| AST (IU/L) | 101.80±87.90 | 59.20±49.50 | 0.0001* |
| >2×ULN (%) | 208 (58.26) | 140 (39.21) | 0.0000006*[OR=2.16 (1.59-2.95)] |
| ALT (IU/L) | 67.10±46.30 | 57.30±47.40 | 0.0053 |
| >2×ULN (%) | 110 (30.81) | 66 (18.48) | 0.00018*[OR=1.96(1.36-2.83)] |
| ALP (IU/L) | 4420.00±23.60 | 221.00±69.10 | 0.0001 |
| >2×ULN (%) | 172 (48.17) | 135 (37.81) | 0.0065*[OR=1.53(1.12-2.08)] |
| Bilirubin (mg/dL) | 1.70±2.70 | 1.60±5.00 | 0.7396 |
| >1.5 mg/dL (%) | 192 (53.78) | 103 (28.85) | 0.00000*[OR=2.87(2.08-3.96)] |
| Albumin (g/dL) | 3.60±0.70 | 3.70±0.90 | 0.0979 |
| <3.5 g/dL (%) | 265 (74.23) | 174 (48.74) | 0.00000*[OR=3.03(2.18-4.21)] |
| >3.5 g/dL (%) | 92 (25.77) | 183 (51.26) | 0.00000*[OR=0.33(0.24-0.46)] |
| AFP (ng/mL) | 6849.00±9652.00 | 5.90±1.20 | 0.0001* |
| <20 ng/mL (%) | 68 (19.04) | 311 (87.11) | 0.00000*[OR=0.03(0.02-0.05)] |
| 20-400 ng/mL (%) | 96 (26.89) | 46 (12.89) | 0.0000043*[OR=2.49 (1.66-3.74)] |
| >400 ng/mL (%) | 193 (54.06) | 0 (0.0) | 0.00000*[OR=UD] |
†, chronic hepatitis cases without HCC;*,statistically significant