Figure 3.

Anti-CD45 RIT of AML-bearing SJL/J mice with and without BMT. (A) Mice were injected with SJL leukemia, followed 2 days later by 0.67 nmol of B10-30F11 labeled with 12 (•) or 24 (▪) µCi ²¹¹At. Control mice received 24 µCi ²¹¹At-B10-rat IgG (♢) or no treatment (○). Mice did not receive BMT in this study, and (†) denotes individual murine deaths due to toxicity. (B) Mice were injected with SJL leukemia and 2 days later with 0.67 nmol of ²¹¹At-B10-30F11 with 12 (•), 20 (♦) or 24 (▪) µCi ²¹¹At. Control mice received 24 µCi ²¹¹At-B10-rat IgG (♢) or no treatment (○). On day +2, mice were given 15 × 10⁶ bone marrow cells via tail vein injection.