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. 2013 Apr 15;8:91. doi: 10.1186/1748-717X-8-91

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Copyright © 2013 Fujisawa et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Dose response curves for proton and carbon ions. Survival fraction per dose obtained by OptiCell™ was calculated from Figure 1 and 2. Cell survival curves in standard cell culture dishes are also plotted. A. photon radiation, gamma-ray survival obtained by OptiCell™ was described by closed circles. Standard survival assay for x-ray was described by closed triangles and gamma-rays was described by open circles. B. proton, closed triangles represent OptiCell™ survival and open triangles represent standard survival. C. carbon ions, closed squares represent LET 13–20 keV/μm, open circles represent LET 20–30 keV/μm, closed circles represent LET >30 keV/μm obtained by the OptiCell™ system. Open triangles represent monoenergetic carbon ions LET 70 keV/μm. Error bars indicate standard errors of the means from as many as four independent experiments.