Table 3.
Summary of DVH-based analysis for OARs and healthy tissue
Organ/Structure | Parameters | Plans | Value (Mean±SD) | P-value |
---|---|---|---|---|
Ipsilateral lung |
V5 |
All |
65%±8% |
|
|
|
Integrated |
67%±9% |
0.005 |
|
|
Segmented |
61%±7% |
|
|
V20 |
All |
28%±2% |
|
|
|
Integrated |
28%±3% |
0.980 |
|
|
Segmented |
28%±2% |
|
|
Dmean (Gy) |
All |
15.06±1.66 |
|
|
|
Integrated |
15.11±1.54 |
0.658 |
|
|
Segmented |
14.93±1.99 |
|
Contralateral lung |
V5 |
All |
12%±11% |
|
|
|
Integrated |
14%±12% |
0.157 |
|
|
Segmented |
9%±8% |
|
|
Dmean (Gy) |
All |
2.26±1.32 |
|
|
|
Integrated |
2.58±1.43 |
0.019 |
|
|
Segmented |
1.66±0.83 |
|
Heart |
V5 |
Left-sided lesions |
56%±15% |
|
|
|
Integrated |
60%±13% |
0.001 |
|
|
Segmented |
45%±13% |
|
|
V10 |
Left-sided lesions |
30%±9% |
|
|
|
Integrated |
31%±10% |
0.076 |
|
|
Segmented |
26%±7% |
|
|
V20 |
Left-sided lesions |
13%±6% |
|
|
|
Integrated |
14%±7% |
0.77 |
|
|
Segmented |
13%±4% |
|
|
V30 |
Left-sided lesions |
7%±3% |
|
|
|
Integrated |
8%±4% |
0.21 |
|
|
Segmented |
6%±3% |
|
|
Dmean (Gy) |
Left-sided lesions |
8.69±1.47 |
|
|
|
Integrated |
8.76±1.61 |
0.65 |
|
|
Segmented |
8.54±1.14 |
|
Spinal cord |
Dmax (Gy) |
All |
36.10±5.87 |
|
|
|
Integrated |
37.24±4.55 |
0.009 |
|
|
Segmented |
33.29±7.97 |
|
Ipsilateral humeral head |
Dmean (Gy) |
All |
23.98±9.25 |
|
|
|
Integrated |
28.22±5.60 |
<0.001 |
|
|
Segmented |
12.31±6.99 |
|
Esophagus |
Dnear-max (Gy) |
All |
41.56±7.79 |
|
|
|
Integrated |
41.84±9.15 |
0.85 |
|
|
Segmented |
41.29±6.47 |
|
|
Dmean (Gy) |
All |
11.14±3.11 |
|
|
|
Integrated |
11.22±2.78 |
0.745 |
|
|
Segmented |
10.83±4.27 |
|
Contralateral breast |
Dmean (Gy) |
All |
0.98±0.46 |
|
|
|
Integrated |
1.01±0.48 |
0.418 |
|
|
Segmented |
0.90±0.43 |
|
|
V5 |
All |
2%±1% |
|
|
|
Integrated |
2%±2% |
0.299 |
|
|
Segmented |
1%±1% |
|
Healthy tissue |
EI |
All |
0.30±0.04 |
|
|
|
Integrated |
0.31±0.03 |
0.094 |
Segmented | 0.28±0.05 |
Abbreviations: Vx: percent volume of critical structures receiving a dose of x Gy; EI: external volume index; other abbreviations as in Table 2.