Table 2.
Toxicities related to the study treatment
|
Toxicity |
Grade |
Total |
|||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||
| Hematological |
|
|
|
|
|
| Leukopenia |
3 |
2 |
0 |
0 |
5/11 (45%) |
| Neutropenia |
2 |
2 |
1 |
0 |
5/11 (45%) |
| Anemia |
2 |
0 |
0 |
0 |
2/11 (18%) |
| Thrombocytopenia |
2 |
1 |
0 |
0 |
3/11 (27%) |
| Biochemical |
|
|
|
|
|
| Increased ALT |
6 |
0 |
0 |
0 |
6/11 (55%) |
| Non-hematological |
|
|
|
|
|
| Rash |
4 |
3 |
0 |
0 |
7/11 (64%) |
| Dry skin |
4 |
2 |
0 |
0 |
6/11 (55%) |
| Pruritus |
3 |
0 |
0 |
0 |
3/11 (27%) |
| Alopecia |
6 |
2 |
0 |
0 |
8/11 (73%) |
| Mucositis |
2 |
0 |
0 |
0 |
2/11 (18%) |
| Fatigue |
5 |
2 |
0 |
0 |
7/11 (64%) |
| Anorexia |
7 |
0 |
0 |
0 |
7/11 (64%) |
| Pyrexia |
0 |
0 |
0 |
0 |
0/11 (0%) |
| Weight loss |
0 |
0 |
0 |
0 |
0/11 (0%) |
| Nausea |
9 |
0 |
0 |
0 |
9/11 (82%) |
| Vomiting |
2 |
1 |
0 |
0 |
3/11 (27%) |
| Diarrhea |
2 |
0 |
0 |
0 |
2/11 (18%) |
| Constipation | 5 | 0 | 0 | 0 | 5/11 (45%) |
ALT, alanine transaminase.