Figure 1. Differential extracellular protein amounts in Newman ΔsecDF in comparison to the wild type Newman.
Proteins identified to be significantly and more than two-fold changed in Newman ΔsecDF compared to the wild type Newman. The mean values of four independent experiments are shown with their standard deviation given, except for NWMN_1019 and ScpA, which were only found in two biological replicates. Proteins are colour coded according to the following categories: N-terminal Sec signal peptide (SP), LPXTG-motif, adhesive properties (MSCRAMM and SERAM), immune evasive properties, autolytic properties and membrane proteins. Proteins confirmed below by Western blot analysis are highlighted in bold. *, P<0.05; **, P<0.01; ***, P<0.001.