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. 2013 May 3;8(5):e62830. doi: 10.1371/journal.pone.0062830

Table 1. Details of the 27 sheep with clinical scrapie and chronic inflammation affecting a number of organs.

No. of cases Organ Causative agent Histopathological pattern PrPSc deposition +/−
5 Lung Nematode parasites Lymphofollicular 2/3
3 Lung MVV Lymphofollicular 2/1
3 Lung Nematode parasites Granulomatous and lymphofollicular 1*/2
2 Ileum MAP Granulomatous 0/2
7 Mammary gland MVV Lymphofollicular 5/2
4 Mammary gland MVV Lymphoproliferative/non-lymphofollicular 0/4
3 Mammary gland Foreign body Granulomatous 0/3

Results of PrPSc IHC at the sites of inflammation are also shown. *PrPSc deposition was seen occurring only within newly formed lymphoid follicles, either adjacent or not to granulomatous inflammatory lesions.