Table 1. Details of the 27 sheep with clinical scrapie and chronic inflammation affecting a number of organs.
No. of cases | Organ | Causative agent | Histopathological pattern | PrPSc deposition +/− |
5 | Lung | Nematode parasites | Lymphofollicular | 2/3 |
3 | Lung | MVV | Lymphofollicular | 2/1 |
3 | Lung | Nematode parasites | Granulomatous and lymphofollicular | 1*/2 |
2 | Ileum | MAP | Granulomatous | 0/2 |
7 | Mammary gland | MVV | Lymphofollicular | 5/2 |
4 | Mammary gland | MVV | Lymphoproliferative/non-lymphofollicular | 0/4 |
3 | Mammary gland | Foreign body | Granulomatous | 0/3 |
Results of PrPSc IHC at the sites of inflammation are also shown. *PrPSc deposition was seen occurring only within newly formed lymphoid follicles, either adjacent or not to granulomatous inflammatory lesions.