Skip to main content
. 2013 May 3;8(5):e62830. doi: 10.1371/journal.pone.0062830

Table 3. Cytokine, chemokine, receptor, adhesion molecule, and PrP gene expression levels.

Molecule Histological pattern P-value (P-value <0.05)*
Lymphofollicular Lymphoproliferative/non-lymphofollicular Granulomatous Healthy L vs LnL L vs G L vs H LnL vs G LnL vs H G vs H
LTα 62.83±43.99 10.06±16.24 4.42±4.82 2.21±1.82 0.0031 0.0012 0.0001 0.9761 0.6406 0.8769
LTβ 207.03±198.98 14.56±22.34 9±11.36 2.62±3.51 0.0013 0.0006 0.0000 0.9845 0.2660 0.4530
TNFα 78.91±85.08 24.26±47.44 17.71±25.82 2.75±3.9 0.0711 0.1322 0.0017 0.9888 0.4973 0.3174
LTBR 2.8±1.73 1.9±2.47 2.41±0.47 0.92±0.81 0.4562 0.9988 0.0567 0.5756 0.7172 0.0991
TNFR1 4.16±2.26 1.98±1.93 2.28±0.4 1.14±1.05 0.1490 0.5234 0.0095 0.8462 0.6902 0.2273
CCL19 236.49±175.91 29.29±51.87 20.98±24.8 2.81±5.77 0.0160 0.0366 0.0001 0.9813 0.2878 0.1476
CCL21 6.46±4.59 3.37±3.63 0.95±0.26 1.2±1.75 0.3001 0.0270 0.0079 0.6057 0.9920 0.3872
CXCL12 2.96±1.55 1.62±1.69 2.45±0.38 0.61±0.9 0.1965 0.9811 0.0015 0.3881 0.2034 0.0059
CXCL13 634.69±522.43 25.41±42.71 134.97±240.91 7.81±19.04 0.0022 0.0792 0.0001 0.3986 0.0391 0.6356
CCR7 62.72±33.66 10.22±15.33 9.18±8.41 2.46±5.09 0.0046 0.0096 0.0000 0.9882 0.1955 0.1057
CXCR4 22.3±19.19 5.55±10.19 3.34±1.27 0.98±1.48 0.0213 0.0596 0.0004 0.9629 0.4747 0.2280
CXCR5 50.98±45.78 3.74±4.68 3.11±1.85 2.57±2.29 0.0003 0.0004 0.0000 0.9977 0.9783 0.9321
VCAM1 32.54±51.84 2.41±3.24 7.93±6.48 1.03±2.15 0.0094 0.4340 0.0004 0.2322 0.7084 0.0220
LYVE1 1.73±1.47 0.44±0.75 0.3±0.13 0.16±0.09 0.0398 0.0330 0.0048 0.9998 0.8999 0.9320
PrP 3.42±4.39 1.02±1.45 17.02±4.99 1.13±1.56 0.3832 0.0012 0.3636 0.0001 0.0000 0.9996

For the different groups the data are shown as mean values ± SD. Multiple comparisons were made with Tukey’s test.

*

P<0.05 values were considered to be statistically significant.

L =  lymphofollicular; LnL =  lymphoproliferative/non-lymphofollicular; G =  granulomatous; H =  healthy.