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. 2013 May 3;8(5):e62895. doi: 10.1371/journal.pone.0062895

Figure 3. Dose-dependent apoptosis induction with Dex, MPA, NET-A and P4 in CD4+ T-cells.

Figure 3

PBMCs were treated with vehicle (EtOH), Dex, MPA, NET-A or P4 at the concentrations indicated for 24 hrs at 37°C. Cells were stained and analysed as described for Figure 1. The figure shows pooled results from two independent experiments with samples from three donors. Error bars represent standard deviation. Statistical trend analysis for each dose response was performed by the Wilcox rank-sum test, as further extended by Cuzick [85], and showed a significant trend only for Dex (p<0.001) and MPA (p = 0.047).