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. 2013 May 3;8(5):e62895. doi: 10.1371/journal.pone.0062895

Figure 5. The GR is involved in GC- and Vpr-mediated apoptosis in CD4+ T-cells.

Figure 5

PBMCs were treated with 100 nM Dex or 1 µM RU486 in the absence or presence of 5 µM Vpr peptide (amino acids 52–96) for 24 hrs. A tryptic BSA digest added at an equivalent mass/volume ratio of peptide, served as a control wherever Vpr peptide was present. Cells were obtained and stained as described in the methods. The histogram shows pooled results from two independent experiments with samples from three donors. Statistical significance was determined by one-way ANOVA with Dunnett’s post-test or a paired t-test, where *, **, and *** indicate p<0.05, 0.01 and 0.005 respectively.