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. 2013 May 3;8(5):e62565. doi: 10.1371/journal.pone.0062565

Table 4. Associations of Proportional Genetic Ancestry with Obesity Parameters at Ages 2 and 5.

Age 2 Age 5
N β or OR(95% CI) p-valuec r2 N β or OR(95% CI) p-value r2
BMI Z-score
%European Ancestry 362 0.02(−0.92,0.95) 0.970 <0.0005 312 −0.34(−1.32,0.65) 0.502 0.001
% Native American Ancestry 362 −0.43(−1.36,0.50) 0.361 0.002 312 0.09(−0.89,1.08) 0.850 <0.0005
% African Ancestrya 362 0.28(0.06,0.50) 0.012 0.017 312 0.14(−0.08,0.37) 0.212 0.005
Waist Circumference
%European Ancestry 313 −3.00(−9.72,3.72) 0.380 0.002
% Native American Ancestry 313 1.85(−4.87,8.57) 0.589 <0.0005
% African Ancestry 313 0.75(−0.78,2.28) 0.335 0.003
Obesity Statusb
%European Ancestry 362 0.62(0.07,5.36) 0.663 312 0.83(0.13,5.29) 0.842
% Native American Ancestry 362 0.65(0.08,5.60) 0.699 312 0.86(0.13,5.49) 0.869
% African Ancestry 362 1.91(1.11,3.29) 0.020 312 1.28(0.83,1.96) 0.267
a

Proportional African ancestry was log transformed to normalize the distribution.

b

Children were considered obese if their BMI was at or above 95th percentile of the 2000 CDC sex-specific BMI-for-age growth charts.

c

Using a Bonferonni correction for multiple testing (15 tests), we considered p-values less than 0.003 to be statistically significant.