Table 4. Associations of Proportional Genetic Ancestry with Obesity Parameters at Ages 2 and 5.
Age 2 | Age 5 | |||||||
N | β or OR(95% CI) | p-valuec | r2 | N | β or OR(95% CI) | p-value | r2 | |
BMI Z-score | ||||||||
%European Ancestry | 362 | 0.02(−0.92,0.95) | 0.970 | <0.0005 | 312 | −0.34(−1.32,0.65) | 0.502 | 0.001 |
% Native American Ancestry | 362 | −0.43(−1.36,0.50) | 0.361 | 0.002 | 312 | 0.09(−0.89,1.08) | 0.850 | <0.0005 |
% African Ancestrya | 362 | 0.28(0.06,0.50) | 0.012 | 0.017 | 312 | 0.14(−0.08,0.37) | 0.212 | 0.005 |
Waist Circumference | ||||||||
%European Ancestry | 313 | −3.00(−9.72,3.72) | 0.380 | 0.002 | ||||
% Native American Ancestry | 313 | 1.85(−4.87,8.57) | 0.589 | <0.0005 | ||||
% African Ancestry | 313 | 0.75(−0.78,2.28) | 0.335 | 0.003 | ||||
Obesity Statusb | ||||||||
%European Ancestry | 362 | 0.62(0.07,5.36) | 0.663 | 312 | 0.83(0.13,5.29) | 0.842 | ||
% Native American Ancestry | 362 | 0.65(0.08,5.60) | 0.699 | 312 | 0.86(0.13,5.49) | 0.869 | ||
% African Ancestry | 362 | 1.91(1.11,3.29) | 0.020 | 312 | 1.28(0.83,1.96) | 0.267 |
Proportional African ancestry was log transformed to normalize the distribution.
Children were considered obese if their BMI was at or above 95th percentile of the 2000 CDC sex-specific BMI-for-age growth charts.
Using a Bonferonni correction for multiple testing (15 tests), we considered p-values less than 0.003 to be statistically significant.