TABLE 6.
Individuals with family history of Parkinson’s disease, essential tremor, and Alzheimer’s disease in first-and second-degree relatives
| N | Parkinson’s disease
|
Essential tremor
|
Alzheimer’s disease
|
||||
|---|---|---|---|---|---|---|---|
| 1st degree | 1st or 2nd degree | 1st degree | 1st or 2nd degree | 1st degree | 1st or 2nd degree | ||
| Sex | |||||||
| Male | 92 | 4 (4.4) | 11 (12.0) | 6 (6.5) | 14 (15.2) | 7 (7.6) | 11 (12.0) |
| Female | 70 | 10 (14.3) | 17 (24.3) | 6 (8.6) | 11 (15.7) | 9 (12.9) | 12 (17.1) |
| PD subtype | |||||||
| Akinetic-rigid | 79 | 7 (8.9) | 13 (16.5) | 3 (3.8) | 9 (11.4) | 10 (12.7) | 15 (19.0) |
| Mixed | 19 | 2 (10.5) | 3 (15.8) | 2 (10.5) | 2 (10.5) | 2 (10.5) | 3 (15.8) |
| Tremor-dominant | 64 | 5 (7.8) | 12 (18.8) | 7 (10.9) | 14 (21.9) | 4 (6.3) | 5 (7.8) |
| Age at exam (yr) | |||||||
| <60 | 28 | 1 (3.6) | 8 (25.6) | 0 (0) | 3 (10.7) | 2 (7.1) | 5 (17.9) |
| 60–69 | 40 | 6 (15.0) | 10 (25.0) | 3 (7.5) | 9 (36.0) | 5 (12.5) | 8 (20.0) |
| 70–79 | 69 | 4 (5.8) | 6 (8.7) | 6 (8.7) | 8 (32.0) | 9 (13.0) | 10 (14.5) |
| ≥80 | 25 | 3 (12.0) | 4 (16.0) | 3 (12.0) | 5 (20.0) | 0 (0) | 0 (0) |
| Total | 162 | 14 (8.6) | 28 (17.3) | 12 (7.4) | 25 (15.4) | 16 (9.9) | 23 (14.2) |
Values are expressed as n (%), unless otherwise indicated.
PD, Parkinson’s disease.